However, most generic drugs, although less expensive than the comparable brand-name drug, are as effective and of the same quality as the brand-name drug (see Bioequivalence and Interchangeability of Generic Drugs). In fact, generic drug makers manufacture many brand-name products for companies that control the brand names. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is.
Lexapro is a form of the generic drug citalopram, specifically the s-isomer. Citalopram is sold under the brand name Celexa. Both Celexa and Lexapro are antidepressants that work as selective serotonin re-uptake inhibitors. Because the action of the drug impacts serotonin, avoid any supplements that may interfere with serotonin or magnify the effects of the drug.
Vitamins
You can use multivitamins while you are taking Lexapro or Celexa, but be sure that they do not contain any of the substances that are not permitted. Avoid taking doses of vitamins that exceed the dietary reference intakes to minimize your risk of a negative reaction. Be especially cautious to avoid taking doses above the recommended levels for vitamins A and K because of their potential blood-thinning properties. As always, consult your doctor before you start taking any supplements or make any changes to your prescription drug regimen.
Tryptophan
Do not take tryptophan supplements or mixed supplements that contain tryptophan while you are on Lexapro or Celexa. Tryptophan changes the concentration of serotonin in the brain, magnifying the effects of Lexapro. It may sound as though tryptophan would help Lexapro by increasing its effect, but combining the two places you at risk of developing serotonin syndrome, which is a potentially life-threatening condition. Symptoms of serotonin syndrome range from diarrhea to seizures.
St. John's Wort
Avoid St. John's wort when you are taking Lexapro or any other antidepressant. St. John's wort has the potential to speed up the metabolism of antidepressants. This means that the drugs will leave your system earlier and you will have lower levels in your bloodstream between doses rather than the relatively constant level anticipated by your prescribing physician. Taking St. John's wort also places you at risk of developing serotonin syndrome.
Food and Alcohol
Lexapro and Celexa can be taken either with or without food based on your preferences and schedule. As with most drugs, you should not drink alcohol while you are taking Lexapro or any other antidepressant.
Eplerenone/Potassium Supplements Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
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How the interaction occurs:
When these two medicines are taken together, your body may not process potassium properly.
What might happen:
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Your blood levels of potassium may increase and cause breathing difficulties, chest pain, slow or irregular heartbeat, confusion, or muscle weakness. This interaction may be more severe if you are taking eplerenone for high blood pressure.
What you should do about this interaction:
Contact your healthcare professional (e.g. doctor or pharmacist) as soon as possible about taking these medicines together. Your doctor may want to check the amount of potassium in your blood.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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1.Inspra (eplerenone) US prescribing information. Pfizer, Inc. May, 2018. .